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Good Hope Hospital Eye Clinic
 

Shingles around the eye, Herpes Zoster Ophthalmicus, some Notes

David Kinshuck


Some notes Links Diagram

 


Abbreviations
  • PHN= postherpetic neuralgia
  • ARN = acute retinal necrosis
  • HZO = Herpes zoster ophthalmicus = shingles around the eye
 

Useful leaflets/information
 

 


Some notes

 


Risk of infection
  • elderly and young
  • HIV+ve
  • if young...test for HIV
  • more severe in older patients Ophthalmology
 

 


Systemic antivirals
  • generally this is helpful, preventing or at least reducing PHN
  • occasionally not necessary in younger well patients
  • always use in the elderly and others
  • treat till the vesicles stop coming
  • generally 7-10 days
  • immunosuppressed usually need intravenous acilcoivir (or an equivalaent potent antviral)...eg all leukaemia patients; anyone very ill
  • monitor renal function and reduce dose if renal function reduces
  • Aciclovir/Valciclovir/Famciclovir
  • Birudin is a newer one daily drug
  • traditionally we are told not to start after 3 days of vesicles...but this advice is out of dte/modified: always start if new vesicles are appearing, if immunosuppressed, start even weeks later.
  • Ganciclovir can be used topically
 

 


Systemic steroids

Systemic steroids may be needed. They used to be used, then we were advised they wer unnecessary, but now believe the are sometimes necessary. Use if severe skin bullae proptosis, ophthalmoplegia, optic neuritis, ARN.

 

 


Postherpetic neuralgia
  • At 12 months, 37% >60y; 50% >70y
  • leading cuase of chronic pain/suicide
  • severe distress
  • reduced with early antiviral treatment
  • treat the HZV pain early...this prevents PHN.
  • use opiod analgesics early to prenent pain pathways development
 

 


Cornea/uveitis
  • late keratitis suggests persistent activity
 

 


Parts of the eye affected
 

 

 

The address of this site ('org' changing to 'nhs') is changing from http://www.goodhope.org.uk/departments/eyedept/ to http://www.goodhope.nhs.uk/departments/eyedept/
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