|
all 3 drugs |
advantages |
disadvantages |
lucentis
|
- block the effect of the 'growth factor'
VEGF that causes leakage and new vessel growth
- share similar benefits and side effects
- each injection has 1/100 risk of problems,
some very serious (eg infection)
- all injections probably needed 3-4 times to treat
ARMD
- injections about a month apart
- drugs not yet passed for regular NHS use by NICE
- all 3 are probably best combined with PDT laser
- 10% patients ..worse sight with treatment
- each drug is given as an injection in the eye ('intravitreal')
|
- to be licenced February 2007
- has the most research supporting its use
- studies suggest slightly more effective
- 40% of patients ...improve sight
|
|
avastin
|
- cheaper
- not licenced
- probably nearly as good as Lucentis
|
- ~£20-100 /injection
- not as much research supporting its use
- not likely to be licenced for a while
|
macugen
|
|
- ~£600 per injection
- not quite as effective as Lucentis
|