Occult with PED ARMD

www.goodhope.nhs.uk/departments/eyedept/

Polypoidal choroidal vasculopathy
David Kinshuck

Low vision & Macula Disease

Polypoidal choroidal vasculopathy

The condition is seen as a branching choroidal network of vessels with vascular dilatation. It is more common in Chinese and Afro-Caribbeans.

The choridal neovascularisation often occurs with a serous haemorrhagic PED. It is discussed in more detail here.

Features see
multiple PEDS subretinal haemorrhages visible polyps: deep orange lesions lipid exudates subretinal fluid RPE atrophy peripapillary lesions classic & occult cnv peripheral lesions

Some notes

ICG will identify this condition
PDT any well defined lesions, 80% resolution, although anti-VEGF treatment is routine
if not well defined, anti-VEGF, and then when retina drier proceed with PDT
anti-VEGF not very effective Gomi BJO 2008 limited Lai BJO 2008
Afro-Caribean..female; Asian...male; Caucasian ..bilateral peripapillary
Yanuzzi Argon laser PDT alone Retina 2010
Cackett haemorrhagic ped is predictive of PCV 2010
Cackett, classification
PDT and and anti-vegf combined are effective BJO 2010
there may be polyps in most chronic cnv membranes Eye 2011 FFA was used to identify lesions: perhaps we need to look harder. Combined Retina 2011 Retina 2011
Avastin works Retina 2011 ; Lucentis Retina 2011
assess appearance Eye 11
Natural course unfavourable Retina 2011
Avstin just as effective as Lucentis Eye 2012
choroid is thicker Graefes 2011
larger lesions less responsive BJO 2011

The address of this site ('org' changing to 'nhs') is changing from http://www.goodhope.org.uk/departments/eyedept/ to http://www.goodhope.nhs.uk/departments/eyedept/

page edited October 2011